Epithelial barrier dysfunction in ocular allergy

N Singh, Y Diebold, SK Sahu, A Leonardi - Allergy, 2022 - Wiley Online Library
… whereas claudin-10 was predominant in conjunctival epithelium. Reduced structural
proteins in the conjunctival epithelium in allergic eye disease. The expression of …

Potential biomarkers for allergic conjunctival diseases

N Roy, S Levanon, PA Asbell - Eye & contact lens, 2020 - journals.lww.com
… with conjunctival epithelial cells push conjunctival mast cells … in a decrease in the levels of
MUC5AC levels on the conjunctival … binding protein, as a possible biomarker in ocular allergy, …

Tear and ocular surface disease biomarkers: A diagnostic and clinical perspective for ocular allergies and dry eye disease

T Suárez-Cortés, N Merino-Inda… - Experimental Eye …, 2022 - Elsevier
… have noted a decrease in the apparent number of proteins, in … Allergic conjunctivitis (AC) is
caused by the ocular response … in tears and epithelium in ocular allergy diseases PAC, SAC, …

[PDF][PDF] Immunopathology of allergic conjunctivitis

DI Chigbu, BK Minhas - Eur. Med. J, 2018 - academia.edu
… are members of the G protein-coupled receptors.Histamine is … the conjunctival epithelium
to secrete IL-33, a pro-allergic … of the lower and superior palpebral conjunctiva, respectively. …

Biologics for allergy: therapeutic potential for ocular allergic diseases and adverse effects on the eye

K Fukuda, T Kishimoto, T Sumi, K Yamashiro… - Allergology …, 2023 - jstage.jst.go.jp
… for ocular allergic diseases such as allergic conjunctivitis, … ocular surface with goblet cells
in the conjunctival epithelium … reportedly have dry eye conditions with reduced goblet cell …

Ocular pharmacology of tear film, dry eye, and allergic conjunctivitis

S Gulati, S Jain - Pharmacologic Therapy of Ocular Disease, 2017 - Springer
conditions that compromise lid apposition or decrease blink … , mucins (glycosylated proteins
produced by epithelial cells), … epithelial cell necrosis; the effect increases with decreased tear …

[HTML][HTML] Allergic conjunctivitis-induced retinal inflammation promotes myopia progression

CC Wei, YJ Kung, CS Chen, CY Chang, CJ Lin… - …, 2018 - thelancet.com
… increased the expression of myopia-related tissue-remodeling proteins. (a) … corneal epithelial
cells (CEP) with TNF-α or IL-6 lowered the TEER, and the TEER was further lowered with …

[HTML][HTML] Therapeutic targets in allergic conjunctivitis

BA Labib, DGI Chigbu - Pharmaceuticals, 2022 - mdpi.com
… The conjunctival epithelial layer is a non-keratinized mucous … Cytokines are small, secreted
cell-signaling proteins that are … in the conjunctiva to reduce conjunctival hyperemia and …

[HTML][HTML] Resolvin D1 treatment on goblet cell mucin and immune responses in the chronic allergic eye disease (AED) model

DR Saban, RR Hodges, R Mathew, NJ Reyes, C Yu… - Mucosal …, 2019 - Elsevier
… actions in conjunctival immune response and a decrease in … Multiplex cytokine analysis was
performed on protein isolates … lacrimal gland and conjunctival epithelial cell electrolyte and …

Clinical implications of mast cell involvement in allergic conjunctivitis

D Elieh Ali Komi, T Rambasek, L Bielory - Allergy, 2018 - Wiley Online Library
… TNF-α induces the IL-8 release from conjunctival epithelial … (TET) to reduce the symptoms
of allergic conjunctivitis. Its … response through binding to the intracellular receptor protein